There are over 120 different cannabinoids found inside hemp that haven’t been discovered in any other plant outside of cannabis, making hemp a truly unique plant indeed. In this article we'll explore the types of cannabinoids and how the research tells us about their effects on human health and longevity.
Keep in mind, the term cannabis is a genus of plant that includes both marijuana and hemp. Each plant has its own different chemical composition, or different ratio of cannabinoids. One of the key differences of hemp is that it contains exceptionally low levels of tetrahydrocannabinol THC (the cannabinoid associated with medical marijuana and the “high” users experience).
Although THC is most widely seen as the compound found inside of cannabis, there are far more varieties of cannabinoids than most people realize, each with their own distinctive qualities and benefits. We do our best to retain as many cannabinoids as possible in our full spectrum whole plant hemp oil.
Cannabidiol CBD, is one of the most popular cannabinoids as of late with its recent explosion onto the medical scene for its use in conditions such as chronic pain, inflammation, seizures, neurological disorders, anxiety disorders, cancer treatment, skin conditions, and metabolic conditions. Some varieties of medical marijuana contain high levels of both THC and CBD, helping to balance out the psychoactive states that can occur when a product is high in THC without CBD present.
The ECS (Endo-Cannabinoid System) is the master key that brings balance to all other systems in the body, from circulatory, digestive and reproductive to the endocrine system. An inactive ECS puts all other systems at risk of imbalance and disturbance.
Currently, there is a lot of research going into CBD and its applications for benefiting human health. With CBD’s powerful benefits, it makes one wonder about the other 120+ cannabinoids and their own individual unique benefits to us all.
THCA has a similar ring to it as THC, but they are entirely different. Here’s why. When the hemp plant is dried or heated, it begins going through the decarboxylation process. This turns THCA into THC.
Early research is showing promise with THCA and its effectiveness in protecting brain degeneration, treating inflammation, and preventing general nausea symptoms and loss of interest in eating, as well as stopping the growth of cancer cells.
Brain degeneration protection could be helpful in cases of Alzheimer’s, Parkinson’s or other neuro-degenerative brain conditions.
Inflammation treatment could be of value in those suffering from chronic pain.
Nausea and appetite loss could show promise with those undergoing chemotherapy or other treatments that result in nausea and a general loss of appetite.
Similar to CBD, THCA binds to the ECS receptors CB-1 and CB-2.
CBG is also found in high concentrations in the hemp plant and doesn’t affect mental processes. CBG has shown to be of assistance with those suffering from chronic pain disorders, inflammation, bone growth stimulation, brain cell stimulation, depression, seizures, insomnia, poor appetite and bacterial infections.
Bone growth stimulation could prove valuable in those suffering from osteoporosis and other bone and joint disorders.
Seizures can prove helpful in those with epilepsy or related neurological disorders.
Bacterial infections could be especially of value in the treatment of antibiotic-resistant strains of bacteria.
CBG is current being assessed for its success in treating glaucoma, IBS, Huntington’s disease, MRSA, and in blocking the growth of cancer cells.
CBDA is the precursor to CBD and it doesn’t seem to interact with the ECS directly. Instead, research is showing that CBDA affects the non-endocannabinoid receptors and systems.
CBDA has been shown to suppress the COX-2 enzyme through its anti-inflammatory properties. The inhibition of COX-2 has shown promise in the reduction of breast cancer cell growth. CBDA activates the serotonin receptors which can help alleviate depression and anxiety. Serotonin also helps manage general nausea and vomiting, which can help increase appetite. Strains of medical marijuana can be bred to contain high levels of this cannabinoid to create more laser-targeted treatment options for those wanting to experience the effects of cannabis.
Differentiating Acidic & Non-Acidic CannabinoidsAcidic compounds like THCA and CBDA are precursors to other compounds. Sometimes they are referred to as the “stem cells”, acidic chemicals are the building blocks that can create an unlimited amount of the same compounds or other types of chemicals with differentiation.In this particular case, when heat or light is applied to an acidic cannabinoid, it converts into a non-acidic cannabinoid.Currently, some of the research shows that non-acidic forms have stronger medicinal benefits than acidic, while others strongly claim the opposite. Interest and the ever-expanding research into acidic compounds is showing that they bring advantages to the user as well. The acidic compounds are crucial, as they create a large variety of cannabinoids within the plant. Studies show that acidic and non-acidic compounds work well together within the body.
Cannabinol CBN is a strong candidate from the cannabis plant and is best known for its sedative properties and has a far stronger sedative effect than many of the other cannabinoids, without causing a “high.” CBN is extremely powerful in its ability to reduce anxiety and the negative side effects of stress.
Using CBN is showing a lot of promise in treating severe mental health disorders like post-traumatic stress disorder (PTSD). This could prove helpful with assisting war veterans, victims of a car accident or crime, and new mothers suffering from post-natal depression and post-natal PTSD.
Additionally, CBN assists with increasing appetite, controls the growth of cancer cells, and activates the same pain-relieving pathways as THC. CBN also activates the CB-1 and CB-2 receptors of the endocannabinoid system (ECS).
As you can tell, cannabinoids produce varying effects in the body from regulating pain and inflammation, to aiding in stress and sleep management, balancing mood and behavior, and helping regulate hormones. It is our view that cannabinoids have been a part of healthy human functioning since the beginning of time, with our own endocannabinoid system producing an array of cannabinoids on its own including AEA and 2-AG.
We hope this explains some of the other cannabinoids found inside the hemp plant, and that it opens your mind up to the possibility that if these 8 cannabinoids can be so valuable in sustaining and benefiting human health, just imagine what the other 112+ cannabinoids that have still yet to be well researched could do for you.
Rahn, Bailey. “What Is THCA and What Are the Benefits of This Cannabinoid?” Leafly. March 17, 2015. Accessed November 13, 2018. www.leafly.com/news/cannabis-101/what-is-thca-and-what-are-the-benefits-of-this-cannabinoid.
Franciosi, Anthony. “CBG: Everything You Need to Know.” Honest Marijuana (blog). October 12, 2018. Accessed November 13, 2018. honestmarijuana.com/cbg/?age-verified=c34f45b03a.
Biles, Mary. “9 Amazing Facts About CBDa.” Endoca (blog). Accessed November 13, 2018. www.endoca.com/blog/9-amazing-facts-about-cbda/.